Live and Inactivated Influenza Vaccines Induce Similar Humoral Responses, but Only Live Vaccines Induce Diverse T-Cell Responses in Young Children
نویسندگان
چکیده
منابع مشابه
Live attenuated and inactivated influenza vaccines in children.
BACKGROUND Live attenuated influenza vaccine (LAIV) and inactivated influenza vaccine (IIV) are available for children. Local and systemic immunity induced by LAIV followed a month later by LAIV and IIV followed by LAIV were investigated with virus recovery after LAIV doses as surrogates for protection against influenza on natural exposure. METHODS Fifteen children received IIV followed by LA...
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BACKGROUND The immunological bases for the efficacies of the 2 currently licensed influenza vaccines, live attenuated influenza vaccine (LAIV) and inactivated influenza vaccine (IIV), are not fully understood. The goal of this study was to identify specific B-cell responses correlated with the known efficacies of these 2 vaccines. METHODS We compared the B-cell and antibody responses after im...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2011
ISSN: 1537-6613,0022-1899
DOI: 10.1093/infdis/jir436